Tag: benchmarking
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HelixFold-S1 Reports Reaching 1,000-Sample Structure Accuracy With 10 Contact-Guided Samples, Based on Vendor-Reported Retrospective Benchmarks Against the Authors’ Own Earlier Model
Analysis based on information available as of 2026-10-23. 30-second summary What: Ten authors on the journal version, all listed with the PaddleHelix Team at Baidu Inc. (Shenzhen, China), describe HelixFold-S1, published in Nature Machine Intelligence on 2026-07-02. It adds two modules, a Contact Prediction Module and a Contact Conditioning Module, on top of HelixFold3, the…
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A Preprint Benchmark of Six Single-Cell and Spatial Transcriptomics Foundation Models Finds No Overall Winner, on Curated Datasets and Without a Reported Simple-Baseline Comparison
Analysis based on information available as of 2026-08-02. 30-second summary What: A preprint (arXiv:2607.17227, submitted 2026-07-19, q-bio.GN) evaluates six single-cell and spatial transcriptomics foundation models (FMs) under one harmonised framework: Nicheformer, CellPLM, scGPT-spatial, GenePT, scELMo and Novae. Tasks were clustering, supervised annotation, marker-gene concordance and perturbation prediction, across scRNA-seq, spatial transcriptomics and Perturb-seq data. The…
