Tag: SGLT2 inhibitor
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In a 212-Patient Open-Label Trial, a Once-Daily Three-Drug Polypill Capsule Raised Six-Month MRI Ejection Fraction by 3.3 Points Over Enhanced Usual Care; the Lower Confidence Bound Is 0.2 and the Hospitalisation Result Is a Secondary Endpoint
Analysis based on information available as of 2026-10-23. 30-second summary What: POLY-HF (NCT04633005; Pandey et al., Nature Medicine, published 2026-07-02) randomised 212 adults with heart failure with reduced ejection fraction (HFrEF) who were not on target-dose guideline-directed medical therapy (GDMT) to a polypill (108) or enhanced usual care (104), open-label, at two Dallas hospitals. The…
