Tag: siRNA
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Lowering Lp(a) is a solved problem — the RNA pipeline now competes on durability, not on depth
Evidence-first notes on bioscience and deep tech, at the edge of the lab and the market. Information only — not investment advice, not medical advice. The 30-second version What. Four nucleic-acid drugs that shut down hepatic apo(a) production — one antisense oligonucleotide (pelacarsen) and three siRNAs (olpasiran, lepodisiran, zerlasiran) — have already saturated the depth…
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The TTR silencers — siRNA vutrisiran succeeded, ASO eplontersen missed, but the deciding variable was the trial population, not the modality
Evidence-first notes on bioscience and deep tech, at the edge of the lab and the market. Information only — not investment advice, not medical advice. All knockdown, hazard-ratio and subgroup figures are attributed to the sponsoring trial, journal or company; several eplontersen numbers are a company press release rather than peer-reviewed data (noted inline), with…
Uthando Nethemba 